What’s the Difference Between Restylane and Juvederm Lip Fillers?
Both Restylane and Juvederm are used to treat the appearance of aging, as this cosmetic procedure grows in popularity. They both contain hyaluronic acid, which has a plumping effect on the treatment area. The HA effectively serves the purpose of volumizing lips, and getting rid of unwanted wrinkles.
Both of these fillers have the same fundamental ingredients, but there are differences in usage, potential side effects, and cost. They are both great for plumping the skin, with results as long as 12 months.
If you want to know more about these popular dermal fillers to make a well-considered decision, keep scrolling to learn the ins and outs of each option. Let’s compare them directly! (Explore the full range of our genuine Dermal Filler supplies.)
Comparing These Lip Fillers
As mentioned before, both Restylane and Juvederm have hyaluronic acid and are non-surgical procedures. These dermal fillers also contain lidocaine to reduce pain during the process.
Both lip filler brands have different formulas that are precisely designed for the lips. And because there are no issues with them, they have been approved by the U.S. Food and Drug Administration (FDA). Both are effective at plumping the skin, often for up to 12 months.
About Restylane Kysse
Restylane Kysse is a dermal lip filler, used as a part of a cosmetic procedure. As per the official website, this was the first-ever lip filler to have gained FDA approval. The filler provides smooth, silky, and natural-looking lips. Not just that, it can be used to augment the lips as well. Many injectors are curious about how these two popular options compare for lip treatments. Often it comes down to personal opinion.
Juvederm Ultra or Volbella XC for lips
This brand comes in two types of lip fillers. Ultra XC, which is for lip augmentation, and Volbella XC, which is to increase the volume of the lips and create or make more prominent the vertical lip lines.
How long do both procedures take?
Both procedures take just a few minutes each. But, it is important that patients have follow-up sessions in the future to maintain the effects on your lips.
Duration of the First Option
The estimated time for an injection session is between 15 to 60 minutes. The reason for that is lips are a lot smaller than other injection areas, seen in other aesthetic treatments. Hence the duration may fall on the lower end of the scale. The effects, however, show up a couple of days after the procedure.
Duration of the Second Option
Usually, this injection procedure takes just as much time as the alternative. The only difference is that, unlike the previous option, these lip results can be seen instantly.
Results Comparison
Thanks to the hyaluronic acid, both dermal fillers are well-known to produce smooth and plumping effects. However, note that one option usually lasts a little longer and shows results faster than the other.
With the first filler, results come into play a few days after the procedure. And they also start wearing off after approximately ten months.
The second option’s results, on the contrary, are instantly visible on the lips after the procedure. The results of the lip filler last for about a year, in average cases.
Who should use these lip fillers?
Even though the FDA has approved both options, it still does not mean that they are suitable for everyone. There are individual risk factors for both dermal lip fillers.
There is a standard rule, though: all dermal fillers are off-limits for pregnant women due to unexplored hazards.
Candidates for the First Filler
Kysse is only a viable option for 21-year-olds and older. Also, this lip procedure might not be suitable for you if you have:
- Allergies with hyaluronic acid or lidocaine
- Inflammatory skin conditions like eczema
- Bleeding disorders
Candidates for the Second Filler
Similar to the first option, this treatment is also for adults starting from 21 years of age. And just like the alternative, your provider will not suggest this lip treatment if you have any allergies mentioned above.
Side effects of lip fillers
Even though both fillers have been declared safe, it does not mean that they are totally risk-free. Minor side effects are always possible.
Side effects of the First Option
Minor side effects of Kysse are:
- Redness
- Swelling
- Tenderness
- Bruising
Major side effects are:
- Hyperpigmentation – skin changing color
- Infections
- Necrosis – the death of surrounding skin tissues
Even though the major side effects are rare, they are still possible. And there might be an increased risk of side effects if you:
- Smoke
- Have bleeding disorders
- Have inflammatory skin conditions
Side effects of the Second Option
This filler also carries the same risk of side effects as the alternative, like redness and swelling. But some people have also felt pain and numbness. The Volbella XC formula can sometimes also cause dry skin.
There are a few severe yet rare side effects. They are:
- Hyperpigmentation
- Scars
- Necrosis
Even though infections and other allergic reactions are also rare, they are still possible.
How to prevent the side effects?
After both procedures, there are a few things patients can do to prevent side effects. Try to avoid strenuous activities, alcohol consumption, and avoid too much exposure to the sunlight or tanning beds for the first 24 hours at the very least.
The makers of the first product have suggested staying away from extremely cold weather conditions until the swelling and redness are there. The manufacturer of the second option, on the other hand, have recommended that people avoid extreme heat.
On average, minor side effects caused by lip treatment go away in about one to two weeks. In treating lip lines, patients can expect the side effects to leave within seven days, while if patients are having their lips plumped, the side effects can remain for up to 14 days.

About the Author: Doris Dickson is a specialist writer for Health Supplies Plus, focusing on the aesthetic medicine industry. She diligently researches cosmetic treatments and products to provide clear, concise information relevant to licensed medical professionals. Her work supports Health Supplies Plus’s commitment to being a reliable informational resource and trusted supplier for the aesthetic community.
Disclaimer: The content provided in this article is intended for informational purposes only and is directed towards licensed medical professionals. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment, nor does it constitute an endorsement of any specific product or technique. Practitioners must rely on their own professional judgment, clinical experience, and knowledge of patient needs, and should always consult the full product prescribing information and relevant clinical guidelines before use. Health Supplies Plus does not provide medical advice.
