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Restylane Silk vs Juvederm
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Restylane Silk is a crystal clear and colorless injectable soft tissue dermal filler formulated by Q-Med, which is a subsidiary of Galderma. It consists of 20mg/ml of cross-linked and non-animal stabilized hyaluronic acid (NASHA) molecules. The resulting gel has a smooth consistency and is an ideal choice for lip enhancement.

Juvederm is a brand of hyaluronic acid-based dermal fillers. Like Restylane, Juvederm has a wide range of cosmetic injectables available to medical professionals. Each of these dermal fillers is designed to address specific concerns.

Included in the Juvederm range is Juvederm Volbella, a similar dermal filler to Restylane Silk. Volbella contains 15mg/ml of cross-linked hyaluronic acid from a non-animal source. Patients love this filler due to its long-lasting results high efficacy.

Where areas are Restylane Silk and Juvederm good for?

Restylane Silk and Juvederm Volbella are both indicated for injection into the perioral area and lip augmentation. Due to the preferable qualities of these formulations, these fillers are usually chosen based on practitioner preference – Restylane Silk and Volbella are popular choices to rejuvenate the lip area. Not only can they plump up the lips, but they can also get rid of vertical lip lines without adding too much volume, smoker’s lines, and other perioral wrinkles.

How does Restylane Silk compare with Juvederm Volbella?

Though both brands share the same active ingredient, they have different gel consistencies and in turn different treatment outcomes. Compared to the biphasic nature of Restylane Silk, in which the NASHA molecules are homogenously suspended in a non-cross-linked hyaluronic acid matrix, Juvederm dermal fillers are monophasic. They are made of a single phase of hyaluronic acid molecules tightly bound to together.

A randomized study involving 221 test subjects seeking lip augmentation from 14 investigational centers found that Restylane Silk is both effective and safe. These patients received Restylane Silk injections for the treatment of thin lips and perioral lines (as required) or no treatment at all (control group). Of the patients, 133 underwent a repeat treatment session with Restylane Silk after six months. Approximately 98% of these subjects reported significant improvement in lip fullness two weeks after the initial injection session. In addition, 76% of the test subjects still experienced improvements in both their upper and lower lips six months after the first treatment session. Patients experiencing perioral lines also experienced significant aesthetic improvements following the injection of this filler.

In comparison, a randomized study involving 280 participants receiving either Juvederm Volbella or Restylane-L found that patients prefered Juvederm Volbella. Of the participants, 90% of the Juvederm Volbella group reported being very satisfied at the three month mark. As well, the manufacturer reports that results can last for up to 12 months.

Based on clinical research, there is also a possibility that Juvederm induces fewer inflammatory responses.

Which filler is most recommended for lip augmentation?

Clinical evaluation of these fillers demonstrate that Restylane has a higher level of stiffness compared to Juvederm fillers. As such, Restylane is a better choice for sculpting lips that have thinned with age or are riddled with perioral lines. However, since certain Juvederm fillers are more cohesive and have a higher spreadability compared to Restylane Silk, they are more suitable for adding plump volume to the lips. Both dermal fillers are extremely effective when used for lip rejuvenation. Depending on the patient’s concerns, be it thinning lips or perioral lines, one filler may work best.

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