PhilART, developed by Croma-Pharma, is a series of injectable skin boosters designed for doctors and cosmetic medical professionals, focusing on skin rejuvenation. This article explores two specific variants, PhilART Eye and PhilART Next, detailing their uses, mechanisms, and clinical relevance for eye area and mature skin rejuvenation.
Composition and Mechanism
Both PhilART Eye and PhilART Next are injectable gels consisting of long-chain polynucleotides (PN), derived from natural sources and processed using Polynucleotide High Purification Technology (PN-HPT) to ensure safety and efficacy. Polynucleotides are molecules found naturally in the body, playing a crucial role in cell repair and regeneration. They stimulate fibroblast activity, promote collagen and elastin production, and offer antioxidant properties by scavenging free radicals, enhancing skin elasticity, hydration, and overall quality.
PhilART Eye
PhilART Eye is specifically designed for the eye contour area, addressing dark circles, creping, and fine lines, enhancing hydration and radiance in this delicate area. It contains a lower concentration of polynucleotides (15 mg in 2 ml, or 7.5 mg/ml) to suit the sensitive periorbital region.
Uses and Applications
- Indications: Reducing fine lines, dark circles, and creping around the eyes; improving skin quality in the periorbital area, including eyelids and eyebrow arches.
- Treatment Areas: Eye contour, eyelids, suitable for sensitive skin and delicate areas around the eyes.
Treatment protocols typically involve injectable administration during a 45-minute appointment, with recommendations for 3-4 sessions spaced at 2-6 week intervals for optimal results. It can be used alone or as a preparatory treatment for other aesthetic procedures, such as lasers or fillers, to enhance outcomes.
Administration
- Technique: Administered through multiple small injections, often using microdroplets or linear retrograde methods, to minimize discomfort and ensure even distribution.
- Injection Depth: Intradermal, targeting the superficial layers of the skin around the eyes.
- Needle Size: Typically includes 2 x 30G 1/2 thin-walled needles, as per product specifications.
Expected Results
- Improved skin texture and radiance around the eyes.
- Reduced appearance of fine lines, dark circles, and creping.
- A more refreshed and youthful look, with results noticeable within 30 days post-treatment.
PhilART Next
PhilART Next is designed for mature, dehydrated skin, focusing on correcting medium to deep wrinkles and improving skin quality on the face. It contains a higher concentration of polynucleotides (20 mg in 2 ml, or 10 mg/ml) to target more significant skin concerns.
Uses and Applications
- Indications: Rejuvenating mature skin, correcting medium to deep wrinkles, and treating areas with scars or acne marks.
- Treatment Areas: Face, particularly the middle third, suitable for dehydrated skin showing signs of aging such as fine lines, wrinkles, and fatigue.
Treatment protocols involve intradermal injections, with recommendations for 3-6 sessions spaced at 2-6 week intervals for optimal results. It can be used standalone or in combination with other aesthetic treatments.
Administration
- Technique: Administered through intradermal injections using microdroplets, linear, or fan techniques to ensure even distribution.
- Injection Depth: Intradermal, targeting deeper layers for wrinkle correction and scar treatment.
- Needle Size: Typically includes 2 x 30G 1/2 needles, as per product specifications
Expected Results
- Reduction in the depth of medium to deep wrinkles.
- Improved skin elasticity and hydration, particularly for mature, dehydrated skin.
- Correction of scars and acne marks, leading to a more youthful appearance.
Comparative Analysis
| Product | Concentration (PN) | Recommended Use | Treatment Areas | Injection Technique |
|---|---|---|---|---|
| PhilART Eye | 15 mg in 2 ml | Eye contour, dark circles, fine lines, creping, sensitive skin | Eye contour, eyelids | Microdroplets, linear, superficial |
| PhilART Next | 20 mg in 2 ml | Mature skin, medium to deep wrinkles, scars, acne marks | Face, middle third | Microdroplets, linear, fan, deeper |
This comparison highlights PhilART Eye’s focus on delicate areas with lower concentration, while PhilART Next targets more significant aging signs with a higher concentration.
Safety Profile and Side Effects
Both PhilART Eye and PhilART Next are noted for their high tolerability and low risk of adverse events, supported by their natural origin and advanced purification process. Common side effects may include mild injection site reactions, such as redness or swelling, which are typically transient. Clinicians are advised to review patient medical histories to identify contraindications, such as allergies to fish-derived products, given the polynucleotides are sourced from European freshwater fish intended for human consumption.
Best practices for administration include using appropriate injection techniques to minimize discomfort and ensure even distribution. Post-treatment care involves advising patients on avoiding sun exposure and maintaining skin hydration to optimize results and reduce potential side effects.
Conclusion
PhilART Eye and PhilART Next represent significant advancements in minimally invasive aesthetics, offering targeted solutions for eye area rejuvenation and mature skin concerns, respectively. Their applications are supported by extensive research on polynucleotides, with a strong safety profile and potential for combination therapies. For doctors and cosmetic medical professionals, understanding their science, efficacy, and best practices is crucial for delivering optimal patient outcomes. Licensed medical professionals can buy PhilART products at Health Supplies Plus.