JUVEDERM® ULTRA PLUS XC

Where can I buy this product?

JUVEDERM® ULTRA PLUS XC is available for purchase through Health Supplies Plus by licensed medical practitioners holding a valid medical license. First-time buyers can register an online account by providing required professional information, including medical license verification and a valid shipping address. Account verification is typically completed within 2 business hours, after which you can purchase medical supplies at competitive wholesale pricing. Registered members may also be eligible for volume discounts and receive dedicated customer service support. We are committed to ensuring all products are sourced and sold exclusively to qualified professionals.

Product Information

What is JUVEDERM® ULTRA PLUS XC?

JUVEDERM® ULTRA PLUS XC is a sterile, pyrogen-free, physiological solution of cross-linked hyaluronic acid (HA) gel which is not of animal origin. Manufactured by Allergan (an AbbVie company), it utilizes the established Hylacross® technology, creating a smooth, cohesive gel suitable for addressing moderate to severe facial wrinkles and augmenting the lips.

This formulation contains 24mg/mL of hyaluronic acid cross-linked with BDDE and includes 0.3% lidocaine hydrochloride to enhance patient comfort during the injection procedure. It is indicated for injection into the mid-to-deep dermis for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds) and for injection into the lips and perioral area for lip augmentation.

Storage: JUVEDERM® ULTRA PLUS XC should be stored between 2°C and 25°C (36°F and 77°F). Do not freeze. Protect from light.

Authenticity: Health Supplies Plus guarantees that all JUVEDERM® products are authentic, sourced through appropriate channels, and handled according to manufacturer specifications.

Note: For professional use only.

How does JUVEDERM® ULTRA PLUS XC work?

JUVEDERM® ULTRA PLUS XC employs the Hylacross® technology to provide a robust, yet smooth, cross-linked HA gel. When injected into the appropriate dermal plane, it adds volume to effectively smooth moderate to severe facial wrinkles and folds, such as nasolabial folds and marionette lines, by physically lifting the depressed tissue.

In the lips, JUVEDERM® ULTRA PLUS XC provides noticeable volume for augmentation and can be used to enhance shape and definition. The cohesive nature of the Hylacross® gel allows for controlled placement and durable results. The hydrophilic HA also helps maintain tissue hydration.

Treatment results are typically visible immediately following the procedure. The duration of effect for JUVEDERM® ULTRA PLUS XC generally lasts up to 12 months, though individual results can vary significantly based on patient factors, treatment area, injection technique, and the volume injected. The integrated lidocaine significantly reduces procedure-related discomfort.

Use Instructions

How to inject this product?

JUVEDERM® ULTRA PLUS XC injection must be performed by a licensed medical practitioner trained in dermal filler injection techniques, adhering strictly to aseptic standards. Prior to treatment, conduct a thorough patient consultation, including medical history review, assessment of facial anatomy, discussion of treatment goals, potential outcomes, risks, and contraindications. Prepare the treatment area by disinfecting thoroughly. Administer the filler via injection into the mid-to-deep dermis for correcting facial wrinkles/folds or into the lip mucosa/dermis for lip augmentation, using the appropriate needle size and technique as detailed in the product’s Instructions for Use (IFU). Gentle massage post-injection may aid integration. Discard all used materials, including any remaining gel, needles, and syringes, as biohazardous waste. **Always refer to the official product IFU for complete administration guidelines.**

Who is an appropriate candidate for this dermal filler?

JUVEDERM® ULTRA PLUS XC is indicated for adults (typically 21 years and older, consult local regulations/IFU) seeking:

• Correction of moderate to severe facial wrinkles and folds (e.g., nasolabial folds, marionette lines).
• Lip augmentation for increased volume and definition.

Patient selection should be based on appropriate indications, absence of contraindications, and realistic expectations discussed during consultation.

How long do results last?

JUVEDERM® ULTRA PLUS XC utilizes Allergan’s Hylacross® technology, involving chemical cross-linking with BDDE to create a durable HA gel resistant to degradation. Clinical studies and extensive use indicate that aesthetic results typically last up to one year, although individual duration varies based on factors such as patient metabolism, lifestyle, area treated, and volume injected. The gel gradually biodegrades over time. Repeat treatments can be performed as needed to maintain correction.

What areas can I treat with this product?

JUVEDERM® ULTRA PLUS XC is indicated for treating moderate to severe facial wrinkles and folds, such as nasolabial folds (smile lines) and marionette lines. It is also indicated for lip augmentation, including adding volume and enhancing the definition of the lips and perioral area.

What are the Benefits of this Product?

• Effective Wrinkle Correction: Addresses moderate to severe facial wrinkles and folds like nasolabial folds.
• Lip Volumization: Provides noticeable volume and definition for lip augmentation.
• Hylacross® Technology: Offers a smooth, cohesive, and durable HA gel formulation.
• Clinically Proven Duration: Results typically last up to one year.
• Integrated Lidocaine: Contains 0.3% lidocaine for enhanced patient comfort during injection.
• Extensive Clinical Use: A well-established filler with a long history of use and FDA approval.
• Biodegradable & Reversible: Naturally breaks down over time; effects can be reversed with hyaluronidase if necessary.

Are there any side effects?

Practitioners must consult the complete Instructions for Use (IFU) provided with the product for comprehensive information on indications, contraindications, warnings, precautions, and potential adverse events. It is essential to discuss all potential risks and side effects with patients prior to treatment. Proper injection technique is critical for safety and optimal results.

Common side effects are typically mild to moderate, temporary, and related to the injection site, including:

• Swelling
• Bruising
• Redness
• Tenderness or Pain
• Itching
• Firmness or Lumps/Bumps (usually temporary)

Advise patients on appropriate aftercare, such as avoiding extreme temperatures, strenuous activity, and excessive touching of the treated area for a specified period post-treatment to help minimize these common reactions.

Severe Adverse Events:
As with any dermal filler injection, there are risks of more serious complications. Practitioners must possess thorough anatomical knowledge, particularly of vascular structures, and be prepared to manage complications. Potential severe adverse events include:

• Vascular Occlusion (VO): Accidental injection into a blood vessel can obstruct blood flow, potentially leading to tissue necrosis (tissue death), scarring, or (in rare cases involving facial arteries) blindness or stroke. Prompt recognition and management according to established protocols are crucial.
• Severe allergic reactions (anaphylaxis)
• Inflammation, infection, or abscess formation
• Granuloma or persistent nodule formation
• Migration of filler
• Prolonged pain or numbness
• Herpetic eruptions (cold sores) in susceptible individuals
• Hypersensitivity reactions

Adverse reactions persisting longer than one week, or any signs suggesting VO or infection, require immediate medical evaluation.