RADIESSE® 3ml

Where can I buy this product?

RADIESSE® 3ml is available for purchase through Health Supplies Plus by licensed medical practitioners holding a valid medical license. First-time buyers can register an online account by providing required professional information, including medical license verification and a valid shipping address. Account verification is typically completed within 2 business hours, after which you can purchase medical supplies at competitive wholesale pricing. Registered members may also be eligible for volume discounts and receive dedicated customer service support. We are committed to ensuring all products are sourced and sold exclusively to qualified professionals.

Product Information

What is RADIESSE® 3ml?

RADIESSE® 3ml is a sterile, injectable, subdermal implant manufactured by Merz Aesthetics, supplied in a larger volume syringe. Its active ingredient is synthetic Calcium Hydroxylapatite (CaHA) microspheres (approximately 30%), uniformly suspended in an aqueous carboxymethylcellulose gel carrier (approximately 70%). This formulation is designed for significant soft tissue augmentation, providing both immediate volume and enduring biostimulation.

RADIESSE® is intended for deep dermal or subcutaneous injection to correct moderate to severe facial wrinkles and folds, restore substantial facial volume (e.g., cheeks, temples, jawline), and for correcting volume loss in the dorsum of the hands. It is critical to note that Radiesse® is a CaHA-based filler and is NOT reversible with hyaluronidase.

Storage: Store according to manufacturer guidelines, typically at controlled room temperature between 15°C and 25°C (59°F and 77°F). Do not freeze. Protect from light.

Authenticity: Health Supplies Plus guarantees that all RADIESSE® products sourced are authentic from the manufacturer or authorized distributors.

Note: For professional use only by trained and licensed practitioners experienced in the use of CaHA fillers and deep, large-volume injection techniques, in accordance with local medical device regulations.

How does RADIESSE® 3ml work? (Based on Manufacturer Information)

RADIESSE® provides a distinctive dual mechanism of action for facial rejuvenation and volumization:

1. Immediate Volumization & Lift: Upon injection, the carboxymethylcellulose gel carrier immediately provides physical volume and lift, correcting wrinkles, folds, or contour deficiencies. The 3ml volume allows for more extensive correction in a single session if deemed appropriate.
2. Neocollagenesis (Collagen Stimulation): Over subsequent weeks and months, the CaHA microspheres act as a scaffold, stimulating the patient’s own fibroblasts to produce new Type I and Type III collagen. As the gel carrier is naturally absorbed by the body, this newly formed collagen matrix provides durable, natural-looking structural support and continued volume enhancement.

This biostimulatory effect leads to sustained improvement in skin quality and volume that extends beyond the initial filling effect. RADIESSE® is known for its high viscosity and elasticity (G’), providing excellent lift capacity and robust support, particularly beneficial when larger volumes are required for structural contouring.

Treatment results are immediately visible. The manufacturer suggests a duration of effect often lasting up to 18-24 months or even longer in some individuals, depending on patient factors, treatment area, and the total volume injected. Appropriate anesthesia (e.g., topical, nerve block, or use of Radiesse(+) with lidocaine if available/chosen) is essential for patient comfort.

Indications for Use (Common Applications)

Based on its properties and common clinical use, RADIESSE® 3ml is typically indicated for adults requiring significant volume restoration or contouring:

• Correction of moderate to severe facial wrinkles and folds (e.g., deep nasolabial folds, marionette lines).
• Substantial facial volume restoration and contouring (e.g., cheeks, temples, pre-jowl sulcus, chin, jawline).
• Correction of volume loss in the dorsum of the hands (requiring larger volumes).
• Addressing facial lipoatrophy or significant contour deficiencies.

It necessitates deep dermal or subcutaneous injection techniques. Appropriate patient selection, thorough anatomical knowledge, and consideration of contraindications outlined in the product guidelines are crucial.

Primary Benefits (Based on Manufacturer Claims & Clinical Use)

• Provides immediate, significant volume correction and long-term collagen biostimulation.
• Large 3ml volume suitable for treating extensive areas or requiring substantial augmentation.
• High viscosity and elasticity offer excellent lift and structural support.
• Durable results, often lasting 18-24 months or more.
• Biocompatible CaHA microspheres are gradually metabolized.
• Well-established product with an extensive history of safe and effective clinical use.

Side Effects and Safety Information

Practitioners must obtain and consult the complete product guidelines provided by the manufacturer for comprehensive details on administration, contraindications, warnings, precautions, and potential adverse events before using this product. Discussing all potential risks and side effects with patients is essential, including its non-reversible nature with hyaluronidase. Advanced training in deep injection techniques and thorough anatomical knowledge are mandatory for safe use, especially when administering larger volumes.

Common side effects expected with CaHA filler injections include temporary, injection-site related reactions:

• Swelling (can be significant initially, especially with larger volumes)
• Bruising / Ecchymosis
• Redness / Erythema
• Tenderness or Pain
• Itching
• Firmness or Palpable Lumps/Bumps (CaHA nodules may require specific management)
• Nodules

Severe Adverse Events:
Injecting deep, structural fillers, particularly in larger volumes, carries significant risks. Practitioners must be prepared to manage serious complications. Potential severe adverse events include:

• Vascular Occlusion (VO): Accidental injection into a blood vessel can obstruct blood flow, potentially leading to severe tissue necrosis, scarring, or (in rare cases involving facial arteries) blindness or stroke. As Radiesse is not reversible with hyaluronidase, prevention through meticulous technique and appropriate VO management protocols (excluding hyaluronidase as a primary solvent for the CaHA component) are even more critical.
• Severe allergic reactions or hypersensitivity
• Inflammation, infection, or abscess formation
• Nodule or granuloma formation (CaHA nodules may require different management strategies than HA nodules, e.g., intralesional steroids, surgical excision in refractory cases).
• Migration of microspheres (rare)
• Prolonged pain or numbness
• Herpetic eruptions (cold sores) in susceptible individuals
• Needle jamming (rare, can be related to product viscosity/handling)

Any signs of vascular compromise, infection, hypersensitivity, or persistent adverse reactions require immediate medical evaluation and management according to established best practices.