Karisma RH Collagen FACE

KARISMA represents a significant advancement in aesthetic medicine, moving beyond simple volumization to offer true bio-restitution of the skin. As a Class III medical device, this injectable soft filler is engineered to counteract skin laxity by stimulating the natural regenerative processes of the dermis. Its power lies in a unique trifecta of ingredients, working in synergy to rebuild, hydrate, and protect the skin’s structural integrity.

This formulation is ideal for practitioners seeking to offer their patients a non-surgical solution for improving skin texture, firmness, and elasticity, as well as for contouring and reducing the appearance of wrinkles and scars.

Key Specifications:

• Product Type: Bio-restitutive Soft filler / Collagen Stimulator
• Classification: MD Class III Medical Device
• Manufacturer: Taumedika Srl, Rome, Italy
• Pack Size: 1 x 2ml pre-filled, sterile syringe
• Included Needle: 27G
• Storage: Store at 2–25°C. Avoid freezing and direct sunlight.

The Trifecta of Action: Composition & Mechanism

KARISMA’s efficacy is derived from its three core components, each playing a distinct and crucial role:

• Rh Collagen (200 µg/ml): The engine of rejuvenation. This non-immunogenic Recombinant Human Collagen (polypeptide α1 chain of type I collagen) is produced via innovative transgenic silkworm technology. It stimulates the synthesis of procollagen in fibroblasts, promoting the regeneration of the extracellular matrix.
• High Molecular Weight Hyaluronic Acid: The hydration matrix. Provides immediate hydration, creates an optimal environment for fibroblast proliferation, and delivers a subtle volumizing effect.
• Carboxymethyl Cellulose (CMC): The protective shield. This powerful anti-aging agent inhibits the enzyme hyaluronidase, preventing the degradation of both the injected and the body’s natural hyaluronic acid. It also helps to stabilize the collagen structure.

Clinical Applications & Indications:

• Correction of fine lines and medium-depth facial wrinkles
• Post-traumatic and post-acne scar reduction
• Improvement of skin elasticity, density, and firmness
• Lip contouring and definition
• Rejuvenation of the neck, décolletage, and hands

Treatment Protocol & Administration:

For optimal results, KARISMA follows a clear and straightforward protocol:

• Initial Course: 2 sessions, spaced 30 days apart.
• Maintenance: A follow-up session is recommended after 4 months. The full protocol can be repeated every 6-12 months depending on patient needs.
• Technique: Administer using a micro-wheal technique, injecting into the mid-dermis.
• Results: Initial improvements are visible quickly, with full bio-restitutive effects developing over 30-60 days as new collagen is synthesized.

Safety Profile & Contraindications:

KARISMA’s Rh Collagen is hypoallergenic and non-immunogenic, ensuring a high safety profile. However, treatment is contraindicated for patients with known allergies to any components, active skin infections (e.g., herpes), autoimmune disorders, or who are pregnant or breastfeeding. Avoid intravascular injection. Do not combine with laser treatments or chemical peels in the same session.

Frequently Asked Questions (FAQ)