JUVEDERM® ULTRA 4

Where can I buy this product?

JUVEDERM® ULTRA 4 is available for purchase through Health Supplies Plus by licensed medical practitioners holding a valid medical license. First-time buyers can register an online account by providing required professional information, including medical license verification and a valid shipping address. Account verification is typically completed within 2 business hours, after which you can purchase medical supplies at competitive wholesale pricing. Registered members may also be eligible for volume discounts and receive dedicated customer service support. We are committed to ensuring all products are sourced and sold exclusively to qualified professionals.

Product Information

What is JUVEDERM® ULTRA 4?

JUVEDERM® ULTRA 4 is a sterile, pyrogen-free, physiological solution of highly cross-linked hyaluronic acid (HA) gel which is not of animal origin. Manufactured by Allergan (an AbbVie company), it is part of the Juvéderm Ultra family utilizing the Hylacross® technology, formulated to provide significant volume and correction for deep cutaneous depressions.

This robust formulation contains 24mg/mL of hyaluronic acid cross-linked with BDDE and includes 0.3% lidocaine hydrochloride to enhance patient comfort during the injection procedure. It is indicated for injection into the deep dermis for correction of deep facial wrinkles and folds (such as severe nasolabial folds) and for volume augmentation in areas like the cheeks and chin.

Storage: JUVEDERM® ULTRA 4 should be stored between 2°C and 25°C (36°F and 77°F). Do not freeze. Protect from light.

Authenticity: Health Supplies Plus guarantees that all JUVEDERM® products are authentic, sourced through appropriate channels, and handled according to manufacturer specifications.

Note: For professional use only.

How does JUVEDERM® ULTRA 4 work?

JUVEDERM® ULTRA 4 employs the Hylacross® technology to create a dense, highly cross-linked HA gel with substantial viscosity and cohesivity. This structure provides significant lift capacity and resistance to degradation, making it suitable for addressing deep folds and providing robust volume enhancement.

When injected into the deep dermis or subcutaneous tissue, JUVEDERM® ULTRA 4 physically fills deep wrinkles and folds and augments facial volume where significant structural support is needed, such as in the cheekbones or chin. Its properties allow it to effectively lift tissue and maintain the desired contour. The HA component also contributes to local tissue hydration.

Treatment results are visible immediately. The duration of effect for JUVEDERM® ULTRA 4 typically lasts up to 12 months or potentially longer in some individuals, depending on factors such as metabolism, treatment area, injection technique, and volume injected. The integrated lidocaine significantly improves patient comfort during the procedure.

Indications for Use

JUVEDERM® ULTRA 4 is indicated for adults (typically 21 years and older, consult local regulations/IFU) requiring correction of deep facial wrinkles and folds and significant volume augmentation. Specific applications include:

• Correction of severe nasolabial folds.
• Treatment of deep marionette lines or oral commissures.
• Volume augmentation of the cheeks (malar enhancement).
• Chin augmentation for improved projection.
• Correction of other deep cutaneous depressions requiring substantial volume.

Appropriate patient selection, deep injection technique, and consideration of contraindications listed in the Instructions for Use (IFU) are crucial before treatment.

Primary Benefits

• High viscosity formulation provides significant volume and lift for deep correction.
• Effectively corrects severe facial wrinkles and folds.
• Suitable for substantial volume augmentation (cheeks, chin).
• Utilizes Hylacross® technology for a robust and durable gel.
• Offers immediate, visible volumizing results.
• Contains lidocaine for improved patient comfort during deep injections.

Side Effects and Safety Information

Practitioners must consult the complete Instructions for Use (IFU) provided with the product for comprehensive information on indications, contraindications, warnings, precautions, and potential adverse events. It is essential to discuss all potential risks and side effects with patients prior to treatment. Proper deep injection technique and thorough anatomical knowledge are critical for safety and optimal results.

Common side effects are typically mild to moderate, temporary, and related to the injection site, including:

• Swelling
• Bruising
• Redness
• Tenderness or Pain
• Itching
• Firmness or Lumps/Bumps (usually temporary, may be more pronounced with high volume)
• Nodules

Severe Adverse Events:
As with any dermal filler injection, particularly those involving deep placement or large volumes, there are risks of more serious complications. Practitioners must be prepared to manage complications. Potential severe adverse events include:

• Vascular Occlusion (VO): Accidental injection into a blood vessel can obstruct blood flow, potentially leading to serious consequences such as tissue necrosis (tissue death), scarring, or (in rare cases involving facial arteries) blindness or stroke. Prompt recognition and management are critical.
• Severe allergic reactions (anaphylaxis)
• Inflammation, infection, or abscess formation
• Granuloma or persistent nodule formation
• Migration of filler
• Prolonged pain or numbness
• Herpetic eruptions (cold sores) in susceptible individuals
• Vision abnormalities (as a potential rare consequence of VO)