Category: Synvisc®
Synvisc®
Name | Details | Summary | Image | Stock | Price | Buy |
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SYNVISC ONE® | Show details | SYNVISC ONE® contains hylans in an injectable gel. A single injection of SYNVISC ONE® in the knee or other synovial joint can relieve osteoarthritis symptoms, like pain and inflammation, for about six months. | In stock | $339.00 | ||
SYNVISC® | Show details | SYNVISC® is a viscosupplement gel that contains hylans similar to what is found in synovial fluid. Inject SYNVISC® into the knee or other synovial joints to provide lubrication and mechanical support. | In stock | $329.00 |
Buy Synvisc Online for Comprehensive Knee Osteoarthritis Management
For medical professionals dedicated to providing robust and lasting solutions for knee osteoarthritis, Synvisc represents a cornerstone in viscosupplementation therapy. Known for its high molecular weight and extended duration of effect, Synvisc helps to significantly reduce pain and improve the functional capacity of the osteoarthritic knee. By restoring the crucial lubricating and shock-absorbing properties of the synovial fluid, Synvisc supports patients in regaining mobility and enhancing their quality of life. Health Supplies Plus is your reliable source for authentic Synvisc products, ensuring consistent and quality supply for your practice.
What is Synvisc?
Synvisc refers to a range of sterile, non-pyrogenic, highly viscoelastic solutions of hylan G-F 20, a derivative of hyaluronic acid (HA). It is specifically indicated for the treatment of pain in patients with osteoarthritis of the knee who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics. Synvisc is a high molecular weight hyaluronan, engineered to provide durable and effective viscosupplementation. It is derived from avian sources (chicken crests), which should be noted for patients with related allergies. Synvisc is typically administered as a series of intra-articular injections into the knee joint.
Mechanism of Action: How Synvisc Works
Synvisc’s therapeutic effect in knee osteoarthritis is achieved by supplementing the degraded hyaluronic acid within the synovial fluid of the affected joint. In OA, the natural HA loses its viscosity and elasticity, leading to increased friction, reduced shock absorption, and subsequent pain. When Synvisc is injected directly into the knee joint, its highly viscoelastic hylan G-F 20 helps to:
- Improve Lubrication: It effectively reduces friction between the damaged cartilage surfaces, facilitating smoother joint movement.
- Enhance Shock Absorption: It provides a robust cushioning effect, absorbing mechanical stresses and protecting the joint during movement and weight-bearing activities.
- Restore Viscoelasticity: It helps to normalize the fluid dynamics within the joint, significantly contributing to pain reduction and improved function.
These combined actions provide significant and sustained relief from OA symptoms.
Advantages of Synvisc for Your Practice and Patients
Integrating Synvisc into your treatment protocols for knee osteoarthritis offers several compelling benefits:
- Clinically Proven Efficacy: Decades of clinical use and extensive studies support its effectiveness in relieving knee OA pain.
- High Molecular Weight: Its unique formulation provides superior viscoelasticity, mimicking healthy synovial fluid properties more closely.
- Long-Lasting Pain Relief: A full course of treatment can provide pain reduction lasting for up to six months or even longer in some patients.
- Improved Joint Function: Helps patients regain mobility and perform daily activities with greater comfort and ease.
- Non-Surgical Option: Provides a valuable, minimally invasive alternative for patients seeking to avoid or delay surgery.
- Established Safety Profile: A widely recognized product with a generally favorable safety profile when administered correctly.
- Enhanced Patient Satisfaction: Leads to an improved quality of life for suitable candidates by reducing discomfort.
Who Should Avoid Synvisc Treatment?
While Synvisc is a widely used and generally safe treatment, it is critical for medical professionals to adhere to contraindications to ensure patient safety. Synvisc should not be administered to patients with:
- Known hypersensitivity to hylan preparations, avian proteins, or any components of Synvisc.
- Infections or skin diseases in the area of the proposed injection site.
- Known infections in the knee joint itself or in adjacent anatomical structures.
- Significant venous or lymphatic stasis in the affected limb.
A thorough medical history, particularly inquiring about avian allergies (e.g., feathers, eggs, poultry), and a comprehensive physical examination are essential before initiating treatment with Synvisc.
Estimated Cost & Value for Your Practice
The cost of Synvisc products for your practice is a key consideration. Health Supplies Plus is committed to providing competitive pricing for authentic Synvisc, ensuring that you can offer this highly effective viscosupplementation therapy to your patients in a financially viable manner. While Synvisc treatment typically involves a series of injections, its long-lasting pain relief and improvement in functional mobility can represent substantial value for your patients, potentially reducing the need for chronic oral analgesics and delaying more invasive procedures.
Why and Where to Use Synvisc
Synvisc is specifically indicated for intra-articular injection into the knee joint to treat pain associated with osteoarthritis. It is typically administered as a course of three weekly injections (Synvisc) or a single injection (Synvisc-One), though local protocols may vary based on the specific product. This treatment is best considered for patients experiencing:
- Persistent knee pain due to OA that has not adequately responded to conservative non-pharmacologic therapies and simple analgesics.
- Symptoms of stiffness and reduced range of motion in the knee joint.
- A desire for a non-surgical alternative to manage their chronic knee OA symptoms.
- Suitability based on a thorough medical evaluation by a qualified physician.
Its precise intra-articular delivery ensures that the therapeutic hyaluronan acts directly within the affected joint.
Potential Side Effects
As with any intra-articular injection, patients may experience localized adverse reactions at the injection site. These are generally mild and temporary, and proper patient counseling should include these possibilities. Common reported side effects associated with Synvisc injections include:
- Injection site pain
- Swelling
- Redness
- Bruising
- Joint effusion (fluid accumulation)
- Rarely, a pseudo-septic reaction (acute inflammatory flare)
These symptoms typically resolve spontaneously within a few days. Rare but more serious complications can occur and warrant immediate medical attention.
Post-Treatment Recommendations for Your Patients
To optimize patient comfort and the therapeutic outcome following Synvisc injections, advise your patients on the following:
- Activity Modification: Advise patients to avoid strenuous activities, high-impact exercises, or prolonged weight-bearing on the treated knee for approximately 48 hours following each injection. Light, normal activities are generally permissible.
- Cold Application: Suggest applying an ice pack to the injected knee for 15-20 minutes at a time, several times a day, to help minimize any swelling or discomfort.
- Pain Management: Over-the-counter pain relievers, such as acetaminophen, can be used to manage any localized discomfort.
- Monitor for Adverse Reactions: Instruct patients to promptly report any signs of infection (e.g., severe or worsening pain, excessive warmth, increasing redness, fever) or allergic reactions.
- Complete Course: Emphasize the critical importance of attending and completing the full series of injections (if applicable) for optimal and sustained results.
By ensuring comprehensive patient education and diligent post-treatment care, you significantly contribute to positive outcomes and patient satisfaction with Synvisc therapy.